Ingredient Spotlight

Polygala Root / Yuan Zhi

Traditionally supports: Peaceful sleep, Emotional balance, Mental sharpness, and Inner focus

How It's Used

In Chinese herbal practices, Yuan Zhi is known for calming the spirit, soothing the heart, and clearing mental fog. It has been traditionally used to enhance cognitive function, support restful sleep, and ease feelings of anxiety or restlessness.

From a Western perspective, Yuan Zhi is valued for its cognitive benefits and its role in supporting emotional well-being. Known for its restorative qualities, it is often associated with promoting mental clarity and resilience.

Fun Fact: Yuan Zhi was a favorite among ancient scholars to enhance focus and creativity, and Buddhist monks used it to deepen their meditation practices.

“Yuan Zhi is a staple in my practice for patients dealing with stress, insomnia, or brain fog. It calms the mind while enhancing focus, helping them sleep soundly and think clearly—bringing both clarity and peace.”

- Dr. Liem Le, DAOM, MS

What the research says.

Proven by 7.484 studies (and counting) doctors of all backgrounds can finally agree on the healing properties of this powerful herb.

The discovery of Yuanzhi-1, a triterpenoid saponin derived from the traditional Chinese medicine, has antidepressant-like activity

Yuanzhi-1, a triterpenoid saponin derived from the traditional Chinese medicine, has antidepressant-like activity

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Polygalae Radix: A review of its traditional uses, phytochemistry, pharmacology, toxicology, and pharmacokinetics

More than 140 compounds have been isolated from Yuan Zhi showing neuroprotective, antidepressant, sedative, anti-inflammatory, antiviral, antitumor, antioxidant, antiaging, and antiarrhythmic effects

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Polygala saponins inhibit NLRP3 inflammasome-mediated neuroinflammation via SHP-2-Mediated mitophagy

Polygala root inhibits the NLRP3 inflammasome via SHP-2-mediated mitophagy in vitro and in vivo, which strongly suggests the therapeutic potential of PSS in various neurodegenerative diseases.

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Polygalae Radix: review of metabolites, pharmacological activities and toxicology

Polygalae Radix has rich pharmacological activities in vitro and in vivo, including protective effects on the nervous system, immune system, cardiovascular system and respiratory system, as well as antioxidant and antiepileptic pharmacological activities.

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